Why We Go Beyond
Standard Screening

Traditional check-ups look at surface-level health. We look deeper. 
Most routine screenings only detect a small fraction of potential disease. And while two people may share the same chronological age, their biological age can differ dramatically. 

At our longevity practice, we offer a comprehensive, elevated, and deeply personalized view of your health that goes far beyond standard medicine.

Our clients receive an advanced, multilayered evaluation that includes: 

gut microbiome analysis, epigenetic age measurement, advanced cancer detection, whole-body imaging, metabolic and toxin profiling, fitness and cognitive evaluation to provide a complete, high-definition view of your health today — and tomorrow.

This is health care at its most proactive — and most empowering. 

Begin Your Personalized JourneyWhat To Expect

Why We Go Beyond Standard Screening

Traditional check-ups look at surface-level health. We look deeper. 
Most routine screenings only detect a small fraction of potential disease. And while two people may share the same chronological age, their biological age can differ dramatically. 

At our longevity practice, we offer a comprehensive, elevated, and deeply personalized view of your health that goes far beyond standard medicine. 
Our clients receive an advanced, multilayered evaluation that includes: 
gut microbiome analysis, epigenetic age measurement, advanced cancer detection, whole-body imaging, metabolic and toxin profiling, fitness and cognitive evaluation to provide a complete, high-definition view of your health today — and tomorrow.

This is health care at its most proactive — and most empowering. 

What We Offer — And Why It Matters 

Our clients receive a comprehensive, physician-curated diagnostic evaluation. Each modality is valuable on its own — but together, they create a coherent, actionable understanding of your health.

Gut Microbiome Sequencing[1]

Your gut microbiome is one of the strongest emerging predictors of immunity, metabolic health, inflammation, and biological aging — and its impact is now supported by large-scale human data. 

Key Data

Microbial gene patterns can possibly predict chronological age with high accuracy, forming a “microbiome aging clock” that correlates with healthspan. 
Individuals with high microbial diversity have significantly lower risk of metabolic syndrome, better insulin sensitivity and lower inflammatory markers .
Reduced microbial diversity is associated with severe viral illness.
Increased microbial entropy (a measure of instability) is linked to accelerated epigenetic aging and reduced performance. 

Why It Matters

A diverse, stable microbiome predicts better immunity, metabolic resilience, and slower biological aging — and it’s modifiable.

Epigenetic Age Analysis[2]

We measure how fast you are aging at the cellular level. 

Key Data

Each 5-year increase in epigenetic age acceleration is linked to 8–15% higher mortality risk. 
These markers predict longevity, cognitive health, cardiovascular risk, and overall vitality. 

Why It Matters

 A measurable, trackable way to understand — and improve — your true biological age.

Comprehensive Cardiometabolic & Healthspan Panel

A deep dive into long-term vitality and disease risk, far beyond a standard blood test.

Includes

Advanced lipoproteins
Insulin resistance markers
Inflammatory aging markers
Mitochondrial and metabolic function indicators

Why It Matters

Detects early metabolic drift — often years before diabetes, cardiovascular disease, or weight changes.

Micronutrient & Food Sensitivity Analysis

We evaluate essential vitamins, minerals, amino acids, fatty acids, and immune-mediated food responses. 

Key Data

Up to 35–40% of high-performing adults have clinically significant micronutrient deficiencies. 
Food sensitivities contribute to chronic inflammation, GI symptoms, fatigue, and immune activation. 

Why It Matters  

Precision nutrition and correcting any deficiency leads to better energy, clearer thinking, and optimized cellular recovery.

Total Toxic Load & Oxidative Stress Profile 

Measures heavy metals, environmental pollutants, mycotoxins, and oxidative stress. 

Includes

Research shows cumulative toxic load correlates with accelerated aging, mitochondrial damage, and metabolic dysfunction. 
Oxidative stress biomarkers predict future risk of vascular disease and cognitive decline. 

Why It Matters

We identify hidden biochemical stressors and create detoxification strategies.

Multi-Cancer Early Detection Blood Test[3]

Detects signals from 50+ cancers in a single blood draw — including pancreatic, liver, ovarian, and other cancers with no routine screening. 

Key Data

Adding MCED to standard screening produced a >7× increase in cancers detected. 
Over 50% of detected cancers were stage I or II. 
False-positive rate: ~0.4%. 

Why It Matters  

A powerful early-detection safety net — especially for high-risk, high-performance lifestyles.

Whole-Body MRI[4]

A radiation-free scan of the brain, spine, organs, soft tissue, and vasculature. 

Key Data

In healthy adults, 1 in 9 people had significant findings requiring follow-up or treatment.
2.6% were cancers, 4.8% intracranial aneurysms.
68% of cancers detected do not have standard screening recommendation.
In high-risk hereditary groups, annual WB-MRI has detected 6–10% cancers over time.

Why It Matters

Detects silent threats long before symptoms appear — cancer, aneurysm, early organ disease.

Performance & Cognitive Optimization Testing[5]

Aging is more than biomarkers — it’s how you perform. 

Includes

DEXA for body composition and bone health
VO₂ Max, a gold-standard measure of cardiovascular fitness
Cognitive testing assessing memory, processing speed, executive function

Key Data

VO₂ Max strongly predicts longevity; top-quartile fitness reduces all-cause mortality by up to 55%
Even a modest improvement in VO₂ Max provides significant longevity benefit, research indicating a dose response of each 1-MET increase is linked with 11–17% lower risk of death.
Cognitive scores correlate with vascular risk, inflammation, and aging biology.

Why It Matters  

Your strength, endurance, and cognition form the bedrock of long-term capability.

The Outcome

Clarity, Control, Confidence:
Your 360° Health Perspective 

No single test can capture the full picture of your health. Each assessment is like an individual instrument in an orchestra — valuable on its own, but only when conducted together they do create a coherent, powerful composition.

We craft a precision roadmap tailored to your biology and continuously monitor and refine your plan over time. Our approach integrates gut microbiome analysis, epigenetic age measurement, advanced multi-cancer detection blood test, whole-body imaging, metabolic and toxin profiling, fitness, and cognitive evaluation to provide a complete, high-definition view of your health today — and tomorrow. 

With this layered, data-driven approach, you gain clarity, control, and confidence — empowering you to make proactive, informed choices for a longer, healthier, more vibrant life.

This is for those who want to: 

Uncover risks years before symptoms arise 

Extend health span with precision 

Invest in long-term vitality and resilience 

Maintain peak performance and energy at every stage of life 

Your Experience

Elevated, Private, High-Touch

01

Personalized 

Personalized

Tailored to Your Biology

Your health journey is as unique as your fingerprint. Every recommendation is informed by your genetics, biomarkers, and lifestyle, creating a plan that works with your body, not against it.

02

Board certified Physician-directed 

Board-Certified Physician-Directed

Expert-Guided Interpretation

Every insight is reviewed by Board certified gastroenterologist specialized in longevity medicine. You’ll benefit from sophisticated, science-driven guidance delivered with clarity and confidence.

03

Comprehensive

Comprehensive

Everything Integrated into One Blueprint

We unify diagnostics, therapies, and lifestyle interventions into a single, actionable roadmap. From advanced labs to nutrition, movement, sleep, and hormone optimization, your plan covers every aspect of optimal aging.

04

Effortless 

Effortless

Virtual, Discreet, Concierge-Level

Luxury and convenience converge: your care is delivered virtually, with a high-touch concierge team managing every detail. Discretion, flexibility, and simplicity are built into every step.

Evidence : Peer-reviewed longevity science

Gut Microbiome and Longevity
  • Madison AA, Burd CE, Andridge R, et al. Gut Microbiota Richness and Diversity Track With T Cell Aging in Healthy Adults. J Gerontol A Biol Sci Med Sci. 2024;79(3):glad276. doi:10.1093/gerona/glad276
  • Gopu V, Camacho FR, Toma R, et al. An accurate aging clock developed from large-scale gut microbiome and human gene expression data. iScience. 2023;27(1):108538. Published 2023 Dec 2. doi:10.1016/j.isci.2023.108538
  • Badal VD, Vaccariello ED, Murray ER, et al. The Gut Microbiome, Aging, and Longevity: A Systematic Review. Nutrients. 2020;12(12):3759. Published 2020 Dec 7. doi:10.3390/nu12123759
  • Mateescu DM, Ilie AC, Cotet I, et al. Gut Microbiome Dysbiosis in COVID-19: A Systematic Review and Meta-Analysis of Diversity Indices, Taxa Alterations, and Mortality Risk. Microorganisms. 2025;13(11):2570. Published 2025 Nov 11. doi:10.3390/microorganisms13112570
  • Li R, Kurilshikov A, Yang S, et al. Association between gut microbiome profiles and host metabolic health across the life course: a population-based study. Lancet Reg Health Eur. 2024;50:101195. Published 2024 Dec 28. doi:10.1016/j.lanepe.2024.101195
  • Zhong X, Harrington JM, Millar SR, Perry IJ, O'Toole PW, Phillips CM. Gut Microbiota Associations with Metabolic Health and Obesity Status in Older Adults. Nutrients. 2020;12(8):2364. Published 2020 Aug 7. doi:10.3390/nu12082364
  • Khaledi M, Poureslamfar B, Alsaab HO, et al. The role of gut microbiota in human metabolism and inflammatory diseases: a focus on elderly individuals. Ann Microbiol. 2024;74:1. doi:10.1186/s13213-023-01744-5.
  • Li H, Tang F, Xue H, et al. Phenome-wide multi-omics integration uncovers distinct archetypes of human aging. arXiv [preprint]. 2025:arXiv:2510.12384. Published October 14, 2025. https://arxiv.org/abs/2510.12384
Epigenetic Clocks and Biological Aging
  • Fransquet PD, Wrigglesworth J, Woods RL, Ernst ME, Ryan J. The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis. Clin Epigenetics. 2019;11(1):62. Published 2019 Apr 11. doi:10.1186/s13148-019-0656-7
  • Margiotti K, Monaco F, Fabiani M, Mesoraca A, Giorlandino C. Epigenetic Clocks: In Aging-Related and Complex Diseases. Cytogenet Genome Res. 2023;163(5-6):247-256. doi:10.1159/000534561
  • Jung SY, Pellegrini M, Tan X, Yu H. Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer. Aging (Albany NY). 2025;17(7):1624-1666. doi:10.18632/aging.206276

Multi-Cancer Early Detection (MCED) Blood Test
  • Schrag D, Beer TM, McDonnell CH 3rd, et al. Blood-based tests for multicancer early detection (PATHFINDER): a prospective cohort study. Lancet. 2023;402(10409):1251-1260. doi:10.1016/S0140-6736(23)01700-2
  • GRAIL, Inc. PATHFINDER 2 study: Galleri® multicancer early detection blood test increased cancer detection more than sevenfold when added to USPSTF A and B recommended screenings. Press release. GRAIL, Inc.; October 17, 2025. Initial results presented at ESMO Congress 2025.

Whole Body MRI
  • Basar Y, Alis D, Tekcan Sanli DE, Akbas T, Karaarslan E. Whole-body MRI for preventive health screening: Management strategies and clinical implications. Eur J Radiol. 2021;137:109584. doi:10.1016/j.ejrad.2021.109584
  • Martins da Fonseca J, Trennepohl T, Pinheiro LG, et al. Reply to the Letter to the Editor: Whole-body MRI for opportunistic cancer detection in asymptomatic individuals-a systematic review and meta-analysis. Eur Radiol. Published online November 17, 2025. doi:10.1007/s00330-025-12127-6
  • Dacoregio, Maria Inez et al. “Baseline surveillance in Li Fraumeni syndrome using whole-body MRI: A systematic review and meta-analysis.” Journal of Clinical Oncology (2024): n. pag.
  • Sodde P, Hyder Z, Pugh S, Lalloo F, Martin R, Soh C, Naqvi J, Whitehouse R, Evans DG, Woodward ER. Evaluation of wholebody MRI for cancer early detection in LiFraumeni syndrome. J Med Genet. 2025;62(10):624627. doi:10.1136/jmg2025110704.
  • Prenuvo Polaris Study: Early findings from wholebody MRI cancer screening presented at the American Association for Cancer Research Annual Meeting. Prenuvo, Inc.; 2025. 
VO2 MAX
  • Lang JJ, Prince SA, Merucci K, et al. Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations from 199 unique cohort studies. Br J Sports Med. 2024;58(10):556-566. Published 2024 May 2. doi:10.1136/bjsports-2023-107849
  • Laukkanen JA, Isiozor NM, Kunutsor SK. Objectively Assessed Cardiorespiratory Fitness and All-Cause Mortality Risk: An Updated Meta-analysis of 37 Cohort Studies Involving 2,258,029 Participants. Mayo Clin Proc. 2022;97(6):1054-1073. doi:10.1016/j.mayocp.2022.02.029